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Unlocking New Treatment Horizons for Celiac Disease: PRKCD Revealed as a Promising Target through Mendelian Randomization

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Zhou Jie, Xu Yixin, Wang Haitao, Wang Kun, Chen Chao

Abstract excerpt

INTRODUCTION: Celiac Disease (CeD) is a serious, lifelong autoimmune condition. There remains a significant unmet medical need for effective pharmacological treatments for CeD. METHODS: We utilized summary statistics for 2,888 druggable genes from the eQTLGen Consortium and the FinnGen Consortium for CeD. In our Mendelian Randomization (MR) analysis, we identified genes associated with CeD that had a false...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40910294
DOI: 10.2174/0118715303410531250815124524
PMCID: PMC13284647

Genes

PRKCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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