Article

Glutamate-Glutamine Homeostasis is Perturbed in Neurons and Astrocytes derived from Patient iPSC Models of Frontotemporal Dementia

2020-07-15

Abstract excerpt

<title>Abstract</title> <p>Frontotemporal dementia (FTD) is amongst the most prevalent early onset dementias and even though it is clinically, pathologically and genetically heterogeneous, a crucial involvement of metabolic perturbations in FTD pathology is being recognized. However, changes in metabolism at the cellular level, implicated in FTD and in neurodegeneration in general, are still poorly understood. He...

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Literature Corpus work: c528f899-971d-5446-bdef-c050acd019ef
DOI: 10.21203/rs.2.23638/v3

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