Article

Full-length mRNA sequencing reveals principles of poly(A) tail length control

2019-02-11

Abstract excerpt

<h4>Summary</h4> Although mRNAs are key molecules for understanding life, there exists no method to determine the full-length sequence of endogenous mRNAs including their poly(A) tails. Moreover, although poly(A) tails can be modified in functionally important ways, there also exists no method to accurately sequence them. Here, we present FLAM-seq, a rapid and simple method for high-quality sequencing of entire m...

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Literature Corpus work: c51ecea0-34c8-5e35-99fa-5fb173b8e0a2
DOI: 10.1101/547034

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