Article

CLT-seq as a universal homopolymer-sequencing concept reveals poly(A)-tail-tuned ncRNA regulation

2022-09-13

Abstract excerpt

<h4>ABSTRACT</h4> Dynamic tuning of the poly(A) tail is a crucial mechanism for controlling translation and stability of eukaryotic mRNA. Achieving a comprehensive understanding of how this regulation occurs requires unbiased abundance quantification of poly(A)-tail transcripts and simple poly(A)-length measurement using high-throughput sequencing platforms. Current methods have limitations due to complicated set...

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Literature Corpus work: 2e673171-c238-54a7-be10-d55d537e3575
DOI: 10.1101/2022.09.11.507502

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