Article

l-DOPA stimulates the dopaminergic phenotype in human retina

2020-10-14

Abstract excerpt

Retinal organoids derived from inducible pluripotent stem cells were used to gain insight into the role of l-DOPA during human retinal development. Dopaminergic gene expression was indicated by assessing two dopamine receptors (DRD1 and DRD2 ), DOPA decarboxylase ( DDC ), and tyrosine hydroxylase ( TH ) via quantitative reverse transcription-polymerase chain reaction at various developmental stages. TH transcri...

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Literature Corpus work: c4fb44f7-3e7f-5ab0-917a-074fa1f787f7
DOI: 10.1101/2020.10.14.339366

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