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Article

22-hydroxycholesterol leads to efficient dopaminergic specification of human Mesenchymal Stem Cells

2018-01-18

Abstract excerpt

In the current study, we aim to investigate the neurogenic effect of 22 (R)- hydroxycholesterol (22-HC), on hMSCs obtained from bone marrow, adipose tissue and dental pulp. The effect was evaluated on the basis of detailed morphological and morphometric analysis, expression of genes and proteins associated with maturation of neurons (NF, MAP2, TUJ1, TH), channel ion proteins (Kv4.2 & SCN5A), chemical functionality...

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Literature Corpus work
a618947e-efc3-57ed-b6a0-506812c8586d
DOI
10.1101/250050
Open publication

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