Expression of functional dopaminergic phenotype in purified cultured Müller cells from vertebrate retina.

doi:10.1016/j.neuint.2008.05.002

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Article

Expression of functional dopaminergic phenotype in purified cultured Müller cells from vertebrate retina.

Neurochemistry international - 1 Sept 2008

Kubrusly Regina C C, Panizzutti Rogerio, Gardino Patricia F, Stutz Bernardo, Reis Ricardo A M, Ventura Ana Lucia M, de Mello Maria Christina F, de Mello Fernando G

Abstract excerpt

Purified retina glial Müller cells can express the machinery for dopamine synthesis and release when maintained in culture. Dopamine is detected in cell extracts of cultures exposed to its precursor, L-DOPA. A large portion of synthesized dopamine is recovered in the superfusing medium showing the tendency of the accumulated dopamine to be released. Müller cells purified from developing chick and mouse retinas...

Topics

Animals
Aromatic Amino Acid Decarboxylase Inhibitors
Biomarkers
Cell Differentiation
Cells, Cultured
Chick Embryo
Cyclic AMP
DNA-Binding Proteins
Dopa Decarboxylase
Dopamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Dopamine Plasma Membrane Transport Proteins

Enzyme Inhibitors

Fluorescent Dyes

Mice

Neuroglia

Neurons

Nuclear Receptor Subfamily 4, Group A, Member 2

Phenotype

Source

Open in PubMed

Identifiers

PMID: 18582514
DOI: 10.1016/j.neuint.2008.05.002

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