Article

Role of mitochondrial dynamics in microglial activation and metabolic switch

2020-05-11

Abstract excerpt

<title>Abstract</title> <p>Background Microglia are the endogenous immune cells of the central nervous system (CNS) and act as sensors of injury in the brain, favouring its homeostasis. Their activation and polarization towards a pro-inflammatory phenotype are associated to injury and disease. These processes are linked to a metabolic reprogramming of the cells, characterized by high rates of glycolytic function...

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Literature Corpus work: c4f2b4e8-1bb7-5858-86d3-4b8c60271eca
DOI: 10.21203/rs.3.rs-26982/v1

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