Article

Population-level survey of loss-of-function mutations revealed that background dependent fitness genes are rare and functionally related in yeast

2021-08-27

Abstract excerpt

In natural populations, the same mutation can lead to different phenotypic outcomes due to the genetic variation that exists among individuals. Such genetic background effects are commonly observed, including in the context of many human diseases. However, systematic characterization of these effects at the species level is still lacking to date. Here, we sought to comprehensively survey background-dependent trait...

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Literature Corpus work: c4be68c2-8c36-5397-aed3-8e998cf0c30b
DOI: 10.1101/2021.08.25.457624

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