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Article

Genetic background effects in quantitative genetics: gene-by-system interactions.

Current genetics - 1 Dec 2018

Sardi Maria, Gasch Audrey P

Abstract excerpt

Proper cell function depends on networks of proteins that interact physically and functionally to carry out physiological processes. Thus, it seems logical that the impact of sequence variation in one protein could be significantly influenced by genetic variants at other loci in a genome. Nonetheless, the importance of such genetic interactions, known as epistasis, in explaining phenotypic variation remains a...

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PMID: 29644456
DOI: 10.1007/s00294-018-0835-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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