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Dissecting the genetic etiology of intestinal obstruction: mendelian randomization identifies potential therapeutic targets

2025-02-21

Abstract excerpt

Intestinal obstruction, a prevalent and serious condition, necessitates deeper understanding of its genetic architecture. This study rigorously employed two-sample Mendelian randomization to dissect the causal influence of gene expression on intestinal obstruction risk, leveraging comprehensive summary-level data from eQTLGen and FinnGen GWAS. To enhance causal inference, Summary-data-based Mendelian Randomization...

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Literature Corpus work
c4a8e86d-0ec0-55c3-9f44-f78163c854d3
DOI
10.1101/2025.02.19.25322532
Open publication

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Dissecting the genetic etiology of intestinal obstruction: mendelian randomization identifies potential therapeutic targetsDOI 10.1101/2025.02.19.25322532
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