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Genetic Associations Between Gastrointestinal Diseases and Chronic Kidney Disease: An Integrated Mendelian Randomization and Bioinformatics Analysis.

Iranian journal of kidney diseases - 25 Feb 2026

Li Xinming, Yang Bo, Hou Huihui, Hong Xin, Yang Ming, Chen Juan, Hu Kai, Li Mengjin, Zhou Chenchen, Zhang Liming, Xue Cheng, Mao Zhiguo

Abstract excerpt

INTRODUCTION: Chronic kidney disease (CKD) is a progressive condition with complex genetic and environmental influences. This study aims to investigate the genetic causal relationships between gastrointestinal diseases and CKD using the Mendelian Randomization (MR) approach and bioinformatics analysis. METHODS: We analyzed genetic associations between nineteen gastrointestinal...

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Celiac Disease
Computational Biology
Gastrointestinal Diseases
Genome-Wide Association Study
Inflammatory Bowel Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Malabsorption Syndromes

Mendelian Randomization Analysis

Renal Insufficiency, Chronic

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PMID: 42234915
DOI: 10.61882/ijkd.20.01.9227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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