Article

Topology independent structural matching discovers novel templates for protein interfaces

2017-12-18

Abstract excerpt

<h4>Motivation</h4> Protein-protein interactions (PPI) are essential for the function of the cellular machinery. The rapid growth of protein-protein complexes with known 3D structures offers a unique opportunity to study PPI to gain crucial insights into protein function and the causes of many diseases. In particular, it would be extremely useful to compare interaction surfaces of monomers , as this would enable...

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Literature Corpus work: c49053cc-8061-5337-bd53-e3a0cb82fd66
DOI: 10.1101/235812

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