Article
Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Tuncbag Nurcan, Keskin Ozlem, Nussinov Ruth, Gursoy Attila
Abstract excerpt
Structural details of protein interactions are invaluable to the understanding of cellular processes. However, the identification of interactions at atomic resolution is a continuing challenge in the systems biology era. Although the number of structurally resolved complexes in the Protein Databank increases exponentially, the complexes only cover a small portion of the known structural interactome. In this...
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