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Article

Identification of Protein-Protein Interactions by Detecting Correlated Mutation at the Interface.

Journal of chemical information and modeling - 28 Sept 2015

Guo Fei, Ding Yijie, Li Zhao, Tang Jijun

Abstract excerpt

Protein-protein interactions play key roles in a multitude of biological processes, such as de novo drug design, immune response, and enzymatic activity. It is of great interest to understand how proteins in a complex interact with each other. Here, we present a novel method for identifying protein-protein interactions, based on typical co-evolutionary information. Correlated mutation analysis can be used to...

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PMID: 26284382
DOI: 10.1021/acs.jcim.5b00320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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