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Modeling Binding Affinity of Pathological Mutations for Computational Protein Design.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Romero-Durana Miguel, Pallara Chiara, Glaser Fabian, Fernández-Recio Juan

Abstract excerpt

An important aspect of protein functionality is the formation of specific complexes with other proteins, which are involved in the majority of biological processes. The functional characterization of such interactions at molecular level is necessary, not only to understand biological and pathological phenomena but also to design improved, or even new interfaces, or to develop new therapeutic approaches. X-ray...

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PMID: 27914049
DOI: 10.1007/978-1-4939-6637-0_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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