Article
A compendium of mutational cancer driver genes.
Nature reviews. Cancer - 1 Oct 2020
Martínez-Jiménez Francisco, Muiños Ferran, Sentís Inés, Deu-Pons Jordi, Reyes-Salazar Iker, Arnedo-Pac Claudia, Mularoni Loris, Pich Oriol, Bonet Jose, Kranas Hanna, Gonzalez-Perez Abel, Lopez-Bigas Nuria
Abstract excerpt
A fundamental goal in cancer research is to understand the mechanisms of cell transformation. This is key to developing more efficient cancer detection methods and therapeutic approaches. One milestone towards this objective is the identification of all the genes with mutations capable of driving tumours. Since the 1970s, the list of cancer genes has been growing steadily. Because cancer driver genes are under...
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