Article

Genetic control of the transcriptional response to active tuberculosis disease and treatment

2025-04-14

Abstract excerpt

<h4>Summary</h4> Understanding the functional impact of genomic sequence variants is critical for evaluating the role of genetic variation in the host response during tuberculosis (TB) disease and anti-TB treatment (ATT). Hitherto, there have been no genome-wide in vivo response expression quantitative trait loci (reQTL) studies conducted for active TB and ATT. Here, using longitudinal peripheral blood RNA-seq d...

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Literature Corpus work: c4203c32-ecf2-5f24-8382-b6763cb47cd8
DOI: 10.1101/2025.04.11.648383

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