Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jan 2012

Barreiro Luis B, Tailleux Ludovic, Pai Athma A, Gicquel Brigitte, Marioni John C, Gilad Yoav

Abstract excerpt

Tuberculosis (TB) is a major public health problem. One-third of the world's population is estimated to be infected with Mycobacterium tuberculosis (MTB), the etiological agent causing TB, and active disease kills nearly 2 million individuals worldwide every year. Several lines of evidence indicate that interindividual variation in susceptibility to TB has a heritable component, yet we still know little about the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Dual-Specificity Phosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Linear Models

Share to Mycobacterium tuberculosis

Share to Quantitative Trait Loci

Share to Tuberculosis

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 22233810
DOI: 10.1073/pnas.1115761109
PMCID: PMC3268270

Genes

DUSP14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection.PMID 22233810Read ↗

Genetic control of the transcriptional response to active tuberculosis disease and treatmentSemantic proximity Read ↗

History of tuberculosis disease is associated with genetic regulatory variation in Peruvians.Semantic proximity Read ↗

Genetic control of the transcriptional response to active tuberculosis disease and treatmentSemantic proximity Read ↗

History of tuberculosis disease is associated with genetic regulatory variation in PeruviansSemantic proximity Read ↗

Genetic control of the transcriptional response to active tuberculosis disease and treatmentSemantic proximity Read ↗

Integrative genomics sheds light on the immunogenetics of tuberculosis in cattleSemantic proximity Read ↗

Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells.Semantic proximity Read ↗

<i>Mycobacterium tuberculosis</i>-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis PathogenesisSemantic proximity Read ↗

Integrative genomics sheds light on the immunobiology of tuberculosis in cattleSemantic proximity Read ↗

Common genetic determinants of dynamic human in vivo immune response to <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cellsSemantic proximity Read ↗

Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.