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Exploring functional variation affecting ceRNA regulation in humans

2015-03-22

Abstract excerpt

MicroRNA (miRNA) sponges have been shown to function as competing endogenous RNAs (ceRNAs) to regulate the expression of other miRNA targets in the network by sequestering available miRNAs. As the first systematic investigation of the genome-wide genetic effect on ceRNA regulation, we applied multivariate response regression and identified widespread genetic variations that are associated with ceRNA competition us...

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Literature Corpus work
c41a63b6-b81c-5934-9a40-2542f52dc94d
DOI
10.1101/016865
Open publication

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Exploring functional variation affecting ceRNA regulation in humansDOI 10.1101/016865
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