Article

Identifying Complex lncRNA/Pseudogene-miRNA-mRNA Crosstalk in Hormone-Dependent Cancers

2021-09-20

Abstract excerpt

The discovery of microRNAs (miRNAs) has fundamentally transformed our understanding of gene regulation. The competing endogenous RNA (ceRNA) hypothesis postulates that not only messenger RNAs but also other RNA transcripts, such as long non-coding RNAs and pseudogenes, can act as natural miRNA sponges. These RNAs influence each other’s expression levels by competing for the same pool of miRNAs through miRNA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 31636492-798c-5316-8a22-62093b2df3dd
DOI: 10.20944/preprints202109.0337.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identifying Complex lncRNA/Pseudogene-miRNA-mRNA Crosstalk in Hormone-Dependent CancersDOI 10.20944/preprints202109.0337.v1Read

Analysis of lncRNA-associated ceRNA network in breast cancer: A new insight into the role of GBP1P1 pseudogene in breast cancerSemantic proximity Read

Construction of a Pseudogene‐associated ceRNA Network and Identification of Prognostic Pseudogene Biomarkers for Colorectal CancerSemantic proximity Read

Crinet: A computational tool to infer genome-wide competing endogenous RNA (ceRNA) interactionsSemantic proximity Read

Identification of a novel competing endogenous RNA network linked to the prognosis of prostate cancerSemantic proximity Read

Integrative analysis of a four-component competing endogenous RNA network reveals potential diagnostic and prognostic biomarkers in gastric cancerSemantic proximity Read

Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes.Semantic proximity Read

A ceRNA network of BBOX1-AS1-hsa-miR-125b-5p/hsa-miR-125a-5p-CDKN2A shows prognostic value in cervical cancerSemantic proximity Read

3′-UTR shortening contributes to subtype-specific cancer growth by breaking stable ceRNA crosstalk of housekeeping genesSemantic proximity Read

Increased expression of RCN1P2, TPM3P9, and HSP90AB3P as pseudogenes in gastric cancer linked to proliferative, inflammatory and metastatic pathways through a competing endogenous RNAs network Running Title: Pseudogenes' role in gastric cancer pathogenesisSemantic proximity Read

Construction and Comprehensive Analysis of the Competing Endogenous Rna Network in Endometrial AdenocarcinomaSemantic proximity Read

Construction and investigation of lncRNA-miRNA-mRNA ceRNA network in thymic epithelial neoplasmsSemantic proximity Read

Exploring the ceRNA Network of Differentially Expressed lncRNAs in Gout: A Bioinformatics AnalysisSemantic proximity Read