Article
Evaluating Genetic Regulators of MicroRNAs Using Machine Learning Models
2025-01-14
Abstract excerpt
This study explores the genetic regulators of microRNAs (miRNAs) using an ensemble of machine learning models to predict miRNA expression levels from gene expression data. Employing ridge regression, we accurately predicted the expression of 353 human miRNAs (R 2 > 0.5), revealing robust miRNA-gene regulatory relationships. By analyzing the coefficients of these predictive models, we identified genetic regulators...
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Identifiers and source
- Literature Corpus work
- 47ff7174-73e7-5b45-a662-9e97318dbcd3
- DOI
- 10.1101/2025.01.09.632215