Article

spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape

2022-03-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Motivation</h4> Cancer is one of the leading causes of death worldwide. Despite significant improvements in prevention and treatment, mortality remains high for many cancer types. Hence, innovative methods that use molecular data to stratify patients and identify biomarkers are needed. Promising biomarkers can also be inferred from competing endogenous RNA (ceRNA) networks that capture the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 41d5240b-63fd-5652-92b9-b256c6bb9d68
DOI: 10.1101/2022.03.29.486212

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscapeDOI 10.1101/2022.03.29.486212Read

Discovering lncRNA Mediated Sponge Interactions in Breast Cancer Molecular SubtypesSemantic proximity Read

LMSM: a modular approach for identifying lncRNA related miRNA sponge modules in breast cancerSemantic proximity Read

Scene: Inferring subtype-specific ceRNA modules in breast cancerSemantic proximity Read

Crinet: A computational tool to infer genome-wide competing endogenous RNA (ceRNA) interactionsSemantic proximity Read

Cirscan: a shiny application to identify differentially active sponge mechanisms and visualize circRNA-miRNA-mRNA networksSemantic proximity Read

Network based multifactorial modelling of miRNA-target interactionsSemantic proximity Read

Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes.Semantic proximity Read

lncRNA OSTN-AS1 May Represent a Novel Immune-Related Prognostic Marker for Triple-Negative Breast Cancer Based on Integrated Analysis of a ceRNA NetworkSemantic proximity Read

DysRegNet: Patient-specific and confounder-aware dysregulated network inferenceSemantic proximity Read

CeNETs analysis reveals the prognostic value of a signature integration from five lncRNAs in breast cancerSemantic proximity Read

DisiMiR: Predicting Pathogenic miRNAs Using Network Influence and miRNA ConservationSemantic proximity Read

CorrAdjust unveils biologically relevant transcriptomic correlations by efficiently eliminating hidden confoundersSemantic proximity Read