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Article

Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.

American journal of human genetics - 8 Jun 2012

Gamazon Eric R, Ziliak Dana, Im Hae Kyung, LaCroix Bonnie, Park Danny S, Cox Nancy J, Huang R Stephanie

Abstract excerpt

We sought to comprehensively and systematically characterize the relationship between genetic variation, miRNA expression, and mRNA expression. Genome-wide expression profiling of samples of European and African ancestry identified in each population hundreds of miRNAs whose increased expression is correlated with correspondingly reduced expression of target mRNAs. We scanned 3' UTR SNPs with a potential...

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Identifiers

PMID: 22658545
DOI: 10.1016/j.ajhg.2012.04.023
PMCID: PMC3370272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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