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Systemic analysis identifying PVT1 / DUSP13 axis for microvascular invasion in hepatocellular carcinoma

16 Dec 2022

Abstract excerpt

BACKGROUND: Microvascular invasion (MVI) is an independent detrimental risk factor for tumor recurrence and poor survival in hepatocellular carcinoma (HCC). Competitive endogenous RNA (ceRNA) networks play a pivotal role in the modulation of carcinogenesis and progression among diverse tumor types. However, whether the ceRNA mechanisms are engaged in promoting the MVI process in patients with HCC remains unknown....

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PMID: 36524545
DOI: 10.1002/cam4.5546

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