Article
Exploring genetic associations with ceRNA regulation in the human genome.
Nucleic acids research - 2 Jun 2017
Li Mulin Jun, Zhang Jian, Liang Qian, Xuan Chenghao, Wu Jiexing, Jiang Peng, Li Wei, Zhu Yun, Wang Panwen, Fernandez Daniel, Shen Yujun, Chen Yiwen, Kocher Jean-Pierre A, Yu Ying, Sham Pak Chung, Wang Junwen, Liu Jun S, Liu X Shirley
Abstract excerpt
Competing endogenous RNAs (ceRNAs) are RNA molecules that sequester shared microRNAs (miRNAs) thereby affecting the expression of other targets of the miRNAs. Whether genetic variants in ceRNA can affect its biological function and disease development is still an open question. Here we identified a large number of genetic variants that are associated with ceRNA's function using Geuvaids RNA-seq data for 462...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.