Article
Mechanisms of Selection on Cancer-Causing Mutations
2025-10-15
Abstract excerpt
The mainstream thinking in the somatic evolution of cancer is mainly mutation centered. In contrast, the evolutionary idea that selection rather than mutation is rate-limiting in cancers is a recent realization. So far, however, there are few insights into how selection works on cancer-causing mutations in the context of the tissue microenvironment. A cancer-causing mutant also causes one or more disruptions of no...
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Identifiers and source
- Literature Corpus work
- c4021341-b88b-56a1-91b1-6545ce266c85
- DOI
- 10.32388/6pkd32