Article
Mechanisms of Selection on Cancer-Causing Mutations
2025-09-12
Abstract excerpt
The mainstream thinking in the somatic evolution of cancer is mainly mutation centred. In contrast, evolutionary thinking showing that selection rather than mutation is rate limiting in cancers is an upcoming realization. But so far there are little insights into how selection works on the cancer causing mutations in the context of the tissue microenvironment. A cancer causing mutant also causes one or more disrup...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 160ec10e-0491-53b4-8070-c4e9ac3341d4
- DOI
- 10.20944/preprints202509.1069.v1