Article

CD4 <sup>+</sup> follicular helper-like T cells are key players in anti-tumor immunity

2020-01-09

Abstract excerpt

<h4>ABSTRACT</h4> To determine the nature of CD4 + T cells that provide ‘help’ for generating robust anti-tumor CD8 + cytotoxic T cell (CTL) responses, we profiled the transcriptomes of patient-matched CD4 + and CD8 + T cells present in the tumor micro-environment (TME) and analyzed them jointly using integrated weighted gene correlation network analysis. We found the follicular helper T cell (T FH ) program...

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Literature Corpus work: c3d29aa1-0044-5ce1-8c86-84457972659c
DOI: 10.1101/2020.01.08.898346

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