Article
Tumor heterogeneity and immune-evasive T follicular cell lymphoma phenotypes at single-cell resolution.
Leukemia - 1 Feb 2024
Suma Sakurako, Suehara Yasuhito, Fujisawa Manabu, Abe Yoshiaki, Hattori Keiichiro, Makishima Kenichi, Sakamoto Tatsuhiro, Sawa Aya, Bando Hiroko, Kaji Daisuke, Sugio Takeshi, Kato Koji, Akashi Koichi, Matsue Kosei, Carreras Joaquim, Nakamura Naoya, Suzuki Ayako, Suzuki Yutaka, Ito Ken, Shiiba Hiroyuki, Chiba Shigeru, Sakata-Yanagimoto Mamiko
Abstract excerpt
T follicular helper (TFH) cell lymphomas (TFHLs) are characterized by TFH-like properties and accompanied by substantial immune-cell infiltration into tumor tissues. Nevertheless, the comprehensive understanding of tumor-cell heterogeneity and immune profiles of TFHL remains elusive. To address this, we conducted single-cell transcriptomic analysis on 9 lymph node (LN) and 16 peripheral blood (PB) samples from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
