Article

THE YKI-CACTUS (I <sub>K</sub> Bα)-JNK AXIS PROMOTES TUMOR GROWTH AND PROGRESSION IN DROSOPHILA

2020-08-17

Abstract excerpt

Presence of inflammatory factors in the tumor microenvironment is well known yet their specific role in tumorigenesis is elusive. The core inflammatory pathways are conserved in Drosophila , including the Toll-Like Receptor (TLR) and the Tumor Necrosis Factor (TNF) pathway. We used Drosophila tumor models to study the role of inflammatory factors in tumorigenesis. Specifically, we co-activated oncogenic forms of...

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Literature Corpus work: c3bad836-8a18-5f7f-b495-7600eec72f28
DOI: 10.1101/2020.08.16.253005

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