Article

A Serpin27A-dependent Toll Signaling Underlies Host Genetics of Cancer Resistance in <i>Drosophila</i>

2021-03-14

Abstract excerpt

Cancer resistance varies amongst individuals, although its host genetic underpinnings remain largely elusive. Remissions of sarcomas were first reported following repeated injections of patients with mixtures of killed bacteria—Coley’s toxins—a phenomenon, which was subsequently causally traced to induction of innate immunity. Here we reveal remission of Drosophila epithelial neoplasms by genetically triggered ho...

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Literature Corpus work: 35c1da13-80a8-59f4-9975-8265fd8f351c
DOI: 10.1101/2021.03.13.435228

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