Article

Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repair

2026-04-13

Abstract excerpt

The absence of a cell wall affords animal cells diverse functionality at the cost of acute sensitization to plasma membrane (PM) damage. Thus, animal cells tightly monitor and maintain PM integrity to prevent cell death. Genetic loss of PM repair factors is associated with human diseases such as muscular dystrophy. Despite evidence that annexin and endosomal sorting complex required for transport (ESCRT) proteins...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c39b2066-8ae0-5d9c-9110-6d3be83e88e5
DOI: 10.64898/2026.04.10.717788

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repairDOI 10.64898/2026.04.10.717788Read

Sealing and healing: A two-step model for plasma membrane repair.Semantic proximity Read

The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair.Semantic proximity Read

Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair.Semantic proximity Read

Recombinant annexin A6 promotes membrane repair and protects against muscle injurySemantic proximity Read

ANXA11 mutations in ALS cause dysregulation of calcium homeostasis and stress granule dynamics.Semantic proximity Read

LASER couples damage sensing to ESCRT assembly for lysosome repair.Semantic proximity Read

Do Alix and ALG‐2 really control endosomes for better or for worse?Semantic proximity Read

ANO5 ensures trafficking of annexins in wounded myofibers.Semantic proximity Read

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screensSemantic proximity Read

When membranes need an ESCRT: endosomal sorting and membrane remodelling in health and disease.Semantic proximity Read

Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective.Semantic proximity Read

Calcium as a molecular switch that regulates Annexin A11 N- and C-terminal domains interaction and its role in ALS.Semantic proximity Read