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Article

When membranes need an ESCRT: endosomal sorting and membrane remodelling in health and disease.

Swiss medical weekly - 1 Jan 2016

Alfred Victor, Vaccari Thomas

Abstract excerpt

Originally discovered as regulators of cargo sorting during endosomal trafficking, ESCRT (endosomal sorting complexes required for transport) proteins are emerging as flexible machines that shape the behaviour of membranes throughout the cell. Deregulation of ESCRT activity is observed in neuro-degenerative diseases, virus infection and cancer. However, the mechanisms of pathogenesis involving ESCRTs have not yet...

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Identifiers

PMID: 27631343
DOI: 10.4414/smw.2016.14347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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