Article

Atorvastatin Promotes Bone Formation in Aged apoE–/– Mice through the Sirt1–Runx2 Axis

2020-07-02

Abstract excerpt

<h4>Background: </h4> Statins are the most widely used drugs in elderly patients, the most common clinical application of statins is in aged hyperlipemia patients. There are few studies on the effects and mechanisms of statins on bone in elderly mice with hyperlipemia. The study is to examine the effects of atorvastatin on bone phenotypes and metabolism in aged apolipoprotein E-deficient (apoE –/– ) mice, and the...

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Literature Corpus work: c3992274-bdd6-5c36-a43a-9d9c8378d0a9
DOI: 10.21203/rs.3.rs-26672/v3

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