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Article

Reduced femoral bone mass in both diet-induced and genetic hyperlipidemia mice.

Bone - 1 Dec 2016

Chen Xiang, Wang Chunyu, Zhang Kun, Xie Ying, Ji Xiao, Huang Hui, Yu Xijie

Abstract excerpt

Growing evidence argues for a relationship between lipid and bone metabolisms with inconsistent conclusions. Sphingosine-1-phosphate (S1P) has been recognized as a suitable candidate for possible link between lipid metabolism and bone metabolism. This study was designed to investigate the effects of hyperlipidemia on bone metabolism using diet-induced and genetic-induced hyperlipidemia animal models and to...

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Identifiers

PMID: 27669658
DOI: 10.1016/j.bone.2016.09.016

Genes

LDLR

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