Article

The regulatory effect of miR-181c-5p on the differentiation function of bone marrow mesenchymal stem cells in postmenopausal osteoporotic mice

2022-04-14

Abstract excerpt

<h4>Background: </h4> Osteoporosis (OP) is a metabolic bone disease syndrome for which there is no good treatment. In this study, we investigated the expression changes of miR-181c-5p in osteoporosis-derived BMMSCs, and the role and molecular mechanism in the osteogenic-lipogenic differentiation of BMMSCs. Methods In this study, an OP mouse model was successfully established using the ovariectomy method, and oste...

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Literature Corpus work: 2c8a07ef-db0e-5d05-8cab-a5d00d9c2d23
DOI: 10.21203/rs.3.rs-1453818/v1

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