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Additive effects of cerebrovascular disease functional connectome phenotype and plasma p-tau181 on longitudinal neurodegeneration and cognitive outcomes

2024-07-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> We investigated the effects of multiple cerebrovascular disease (CeVD) neuroimaging markers on brain functional connectivity (FC), and how such CeVD-related FC changes interact with plasma p-tau181 (Alzheimer’s disease (AD) marker) to influence downstream neurodegeneration and cognitive changes. <h4>METHODS</h4> Multivariate associations between four CeVD markers and whol...

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Literature Corpus work
c396b8fb-af32-5d93-840d-b7dd5fb941e4
DOI
10.1101/2024.07.09.602637
Open publication

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Additive effects of cerebrovascular disease functional connectome phenotype and plasma p-tau181 on longitudinal neurodegeneration and cognitive outcomesDOI 10.1101/2024.07.09.602637
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