Article

Neuro-Metabolic and Vascular Dysfunction as an Early Diagnostic for Alzheimer’s Disease and Related Dementias

2025-05-14

Abstract excerpt

Alzheimer’s disease (AD) is the most prevalent neurodegenerative condition characterized by significant cognitive decline. Recent studies suggest that the brain undergoes anatomical and functional restructuring, resulting in neuro-metabolic and vascular dysregulation (MVD) prior to amyloid-β accumulation, which begins at an early age and leads to the onset of AD. Using a retrospective clinical population (N=403) o...

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Literature Corpus work: a487b1fa-62e5-591f-92c0-5e3bda9caf46
DOI: 10.1101/2025.05.12.653558

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