Article

Multimodal Integration of Alzheimer's Plasma Biomarkers, MRI, and Genetic Risk for Individual Prediction of Cerebral Amyloid Burden

2025-05-08

Abstract excerpt

Abstract Alzheimer's disease (AD), the most prevalent neurodegenerative disorder, is marked by the accumulation of amyloid-β (Aβ) plaques. Although cerebral Aβ positron emission tomography (Aβ-PET) remains the gold standard for assessing cerebral Aβ burden, its clinical utility is hindered by cost, radiation exposure, and limited availability. Plasma biomarkers serve as promising non-invasive predictors of cerebra...

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Literature Corpus work: cc96b794-49ef-5e9d-857e-9ee9b845e8e4
DOI: 10.1101/2025.05.07.25326855

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