Article

Emerging Accessibility Patterns in Long Telomeric Overhangs

2021-11-25

Abstract excerpt

We present single molecule experimental and computational modeling studies investigating the accessibility of human telomeric overhangs of physiologically relevant lengths. We studied 25 different overhangs that contain 4-28 repeats of GGGTTA (G-Tract) sequence and accommodate 1-7 tandem G-quadruplex (GQ) structures. Using FRET-PAINT method, we probed the distribution of accessible sites via a short imager strand,...

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Literature Corpus work: c38e9e45-efb6-5c9f-b148-c320fa2b79de
DOI: 10.1101/2021.11.24.469879

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