Article
Differential Transcriptional Programs Reveal Modular Network Rearrangements Associated to Late-Onset Alzheimer’s Disease
2025-02-03
Abstract excerpt
Alzheimer’s disease (AD) is a complex, genetically heterogeneous disorder. The diverse phenotypes associated with AD result from intricate interactions between genetic and environmental factors, influencing multiple biological pathways throughout disease progression. Network-based approaches offer a comprehensive way to assess phenotype-specific states. In this study, we calculated key network metrics to character...
Topics
Open a Topic to create a Post that cites this publication.
- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- Dementia and Cognitive Impairment Research
- Functional Brain Connectivity Studies
- Gene expression and cancer classification
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Nuclear Receptors and Signaling
Identifiers and source
- Literature Corpus work
- c363ce60-9c95-59ec-958d-785830160c6a
- DOI
- 10.20944/preprints202502.0048.v1
