Article

Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease

2019-07-07

Abstract excerpt

Alzheimer’s disease (AD) is a devastating neurological disorder characterized by changes in cell-type proportions and consequently marked alterations of the transcriptome. Here we use a data-driven systems biology approach across multiple cohorts of human AD, encompassing different brain regions, and integrate with multi-scale datasets comprising of DNA methylation, histone acetylation, transcriptome- and genome-w...

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Literature Corpus work: 97d83d62-f580-5b64-9082-93f00cbcc075
DOI: 10.1101/695221

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