Article

Effects of testosterone and estrogen on human CD4+ T-cell subsets during gender-affirming hormone therapy

2026-04-09

Abstract excerpt

<title>Abstract</title> <p>Women have a higher burden of Type 2-driven diseases as well as Type 1-/Type 17-driven autoimmune diseases, suggesting insufficient counterbalancing by regulatory T cells (Tregs) as a possible shared mechanism. We investigated early immunological effects of gender-affirming hormone therapy (GAHT) in 19 transmen and 15 transwomen by analyzing CD4⁺ T-cell subsets before and three months a...

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Literature Corpus work: c35ca641-ab1f-5c4e-aa9c-cf27152eb0a2
DOI: 10.21203/rs.3.rs-9281100/v1

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