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Article

Regulatory T Cell Proportion and Phenotype Are Altered in Women Using Oral Contraception.

Endocrinology - 1 Sept 2022

Moldenhauer Lachlan M, Jin Min, Wilson Jasmine J, Green Ella S, Sharkey David J, Salkeld Mark D, Bristow Thomas C, Hull M Louise, Dekker Gustaaf A, Robertson Sarah A

Abstract excerpt

Regulatory T (Treg) cells are a specialized CD4+ T cell subpopulation that are essential for immune homeostasis, immune tolerance, and protection against autoimmunity. There is evidence that sex-steroid hormones estrogen and progesterone modulate Treg cell abundance and phenotype in women. Since natural oscillations in these hormones are modified by hormonal contraceptives, we examined whether oral contraception...

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Identifiers

PMID: 35786711
DOI: 10.1210/endocr/bqac098
PMCID: PMC9354970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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