Article

Single cell RNA-sequencing reveals an association between testosterone treatment and reduced hormone signaling in the human mammary gland

2026-01-02

Abstract excerpt

Testosterone is the most studied androgen in hormone replacement therapy in postmenopausal women. Many transgender men also receive long-term testosterone replacement therapy (TRT) and have high serum testosterone levels compared to the low levels seen in cisgender women. Compared to other sex hormones such as estrogen and progesterone, the effects of testosterone on the mammary gland have been relatively understu...

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Literature Corpus work: 04cc44a8-f10d-5748-9cf6-a33396d6746e
DOI: 10.64898/2025.12.31.697241

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