Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of aging on the frequency, phenotype, and function of CD4+ T cells in the human female reproductive tract.

Frontiers in immunology - 1 Jan 2024

Shen Zheng, Vom Steeg Landon G, Patel Mickey V, Rodriguez-Garcia Marta, Wira Charles R

Abstract excerpt

Since CD4+ T cells are essential for regulating adaptive immune responses and for long lasting mucosal protection, changes in CD4+ T cell numbers and function are likely to affect protective immunity. What remains unclear is whether CD4+ T cell composition and function in the female reproductive tract (FRT) changes as women age. Here we investigated the changes in the composition and function of CD4+ T cells in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4-Positive T-Lymphocytes

Share to Cervix Uteri

Share to Endometrium

Share to Phenotype

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 39328419
DOI: 10.3389/fimmu.2024.1465124
PMCID: PMC11424415

Genes

CD4
CD69

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of aging on the frequency, phenotype, and function of CD4+ T cells in the human female reproductive tract.PMID 39328419Read ↗

Sex differences matter in the gut: effect on mucosal immune activation and inflammationSemantic proximity Read ↗

Regulatory T Cell Proportion and Phenotype Are Altered in Women Using Oral Contraception.Semantic proximity Read ↗

Effect of aging on the female reproductive functionSemantic proximity Read ↗

Effects of testosterone and estrogen on human CD4+ T-cell subsets during gender-affirming hormone therapySemantic proximity Read ↗

Progesterone Levels Associate with a Novel Population of CCR5+CD38+ CD4 T Cells Resident in the Genital Mucosa with Lymphoid Trafficking PotentialSemantic proximity Read ↗

Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartmentsSemantic proximity Read ↗

Alteration of systemic and uterine endometrial immune populations in patients with endometriosis.Semantic proximity Read ↗

Characterization of peripheral T helper 17 (Th17) cells phenotype in postmenopausal women with estrogen insufficiency.Semantic proximity Read ↗

Toward understanding sexual immune dimorphism in humansSemantic proximity Read ↗

Changes in the proportion of regulatory T cell subpopulations during menstrual cycle and early pregnancySemantic proximity Read ↗

Human uterine lymphocytes acquire a more experienced and tolerogenic phenotype during pregnancy.Semantic proximity Read ↗

Slower immune system aging in women versus men in the Japanese populationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.