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Independent effects of testosterone, estradiol, and sex chromosomes on gene expression in immune cells of trans- and cisgender individuals

2024-10-09

Abstract excerpt

<h4>Summary</h4> The origins of sex differences in human disease are elusive, in part because of difficulties in separating the effects of sex hormones and sex chromosomes. To separate these variables, we examined gene expression in four groups of trans- or cisgender individuals: XX individuals treated with exogenous testosterone (n=21), XY treated with exogenous estradiol (n=13), untreated XX (n=20), and untreat...

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Identifiers and source

Literature Corpus work
94155e3b-7ebd-52cc-9fff-4ee70d5027fe
DOI
10.1101/2024.10.08.617275
Open publication

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Independent effects of testosterone, estradiol, and sex chromosomes on gene expression in immune cells of trans- and cisgender individualsDOI 10.1101/2024.10.08.617275
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