Article

Loss of chromosome Y in regulatory T cells

2023-06-20

Abstract excerpt

<h4>ABSTRACT</h4> Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many forms of cancer. It has been suggested that the association between LOY and disease risk depends on what type of leukocyte is affected with Y loss, with prostate cancer patients showing high...

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Literature Corpus work: c30ffb4d-716f-5342-b3a9-f3ce001a4f3b
DOI: 10.1101/2023.06.17.23291316

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