Article

Loss of chromosome Y in primary tumors

2022-08-22

Abstract excerpt

It has long been recognized that certain cancer types afflict female and male patients disproportionately. The reasons for this disparity include differences in male/female physiology, effect of sex hormones, risk behavior and environmental exposures, and different copy number of the sex chromosomes X and Y. Loss of Y (LOY) is common in peripheral blood cells in aging men, and this phenomenon is associated with se...

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Identifiers and source

Literature Corpus work: 8e5ed413-40f9-57b4-bf19-33d53825b0ca
DOI: 10.1101/2022.08.22.504831

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